Acta Neurol Scand 1991 Sep;84(3):192-6

Does orthotopic liver transplantation heal Wilson's disease? Clinical follow-up of two liver-transplanted patients

Hefter H, Rautenberg W, Kreuzpaintner G, Arendt G, Freund HJ, Pichlmayr R,
Strohmeyer G

Abstract
Two patients with Wilson's disease (WD) underwent orthotopic liver
transplantation, one for subacute liver failure and the other for severe
oesophageal haemorrhage. After transplantation both patients fully recovered
within five months, and copper metabolism returned to normal. Follow-up
examinations were continued for 4 and 6 years. Clinical as well as
electrophysiological testing in these two patients yielded better results than
in most of 12 WD-patients being conventionally treated for a similar period or
even longer